"A rapidly emerging immunotherapy approach is called adoptive cell transfer (ACT): collecting and using patients’ own immune cells to treat their cancer. There are several types of ACT (see “ACT: TILs, TCRs, and CARs”), but, thus far, the one that has advanced the furthest in clinical development is called CAR T-cell therapy.
"Until recently, the use of CAR T-cell therapy has been restricted to small clinical trials, largely in patients with advanced blood cancers. But these treatments have nevertheless captured the attention of researchers and the public alike because of the remarkable responses they have produced in some patients—both children and adults—for whom all other treatments had stopped working."
from National Cancer Institute. 2017 Dec 14. CAR T cells: engineering patients' immune cells to treat their cancers. National Institutes of Health. [accessed 2018 Oct 25]. https://www.cancer.gov/about-cancer/treatment/research/car-t-cells.
Adoptive cell transfer
Solid tumors
CD19
Cytokine release syndrome
Immunotherapy
Immunoglobulin therapy
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